Focal gigantism is 1. The excessive growth of a specific body part such as a hand or foot, as with increased blood supply to that part. 2. The excessive growth of a combination of particular body parts, as is characteristic of a congenital malformation syndrome called the Wiedemann-Beckwith syndrome. Focal gigantism may occur before or after the bones fuse. If it occurs afterwards, it causes disfigurement, as in acromegaly. Surgery for mass reduction may sometimes improve function.