Bubble Boy Disease (Severe Combined Immunodeficiency Disease) (SCID)
Bubble Boy Disease (aka severe combined immunodeficiency disease or SCID) is a combined deficiency of the immune system’s two major weapons — antibodies and T cells — are genetically missing or disabled. Severe combined immunodeficiency disease (SCID) is rare. The chances of a child being born with SCID are about one in 500,000 births. Until recent years, it was always fatal. There are a number of different causes of SCID. Each is caused by a different genetic defect, and each develops along a different pathway. The term “bubble boy” comes from the method by which these children are protected from exposure to pathogenic micro-organisms by isolating them in a plastic tent-like structure, a “bubble.” This is done because any infection in these children is a death sentence.