Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED)

Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED)

Dr. KennedyAutoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED): A genetic autoimmune disease with an extraordinary array of clinical features but characterized most often by at least 2 of the following 3 findings: hypoparathyroidism – underfunction of the parathyroid glands which control calcium, candidiasis (yeast infection), and adrenal insufficiency (underfunction of the adrenal gland). APECED was the first systemic (bodywide) autoimmune disease found due to a defect in a single gene.

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