Antiphospholipid Antibody Syndrome (APLS)
The antiphospholipid antibody syndrome (APLS) is an immune disorder characterized by the presence of abnormal antibodies in the blood associated with abnormal blood clotting, migraine headaches, recurrent pregnancy losses (repeat spontaneous abortions), and low blood platelet counts (thrombocytopenia). These abnormal antibodies are directed against phospholipids. (fats that contains phosphorous). APLS can occur by itself (primary) or be caused by an underlying condition such as systemic lupus erythematosus. About a third of persons with primary APLS have heart valve abnormalities.