Antidiuretic Hormone (ADH)
Antidiuretic hormone (ADH) is a small peptide molecule that is released by the pituitary gland at the base of the brain after being made nearby in the hypothalamus. ADH has an antidiuretic action by promoting the concentration of urine. Inappropriate secretion of ADH results in the inability to put out dilute urine, disturbs fluid and electrolyte balance, and causes nausea, vomiting, muscle cramps, confusion and convulsions. This syndrome may occur in association with oat-cell lung cancer, pancreatic cancer, prostate cancer, and Hodgkin’s disease as well as a number of other disorders. ADH also can stimulate contraction of arteries and capillaries and can cause hypertension. ADH is also known as vasopressin.