Anti-angiogenesis Drugs

Anti-angiogenesis Drugs

Dr. KennedyAnti-angiogenesis drugs include angiostatin and endostatin. They the process of developing new blood vessels (angiogenesis). Angiostatin is a piece of a larger and very common protein, plasminogen, that the body uses in blood clotting. Endostatin is a piece of a different protein, collagen 18, that is in all blood vessels. Both angiostatin and Endostatin are normally secreted by tumors. It is hoped that they will provide the basis for a new class of agents to treat cancer. The original idea of combating cancer in this way came from nutritional medicine about 1990 when shark cartilage was found to contain anti-angiogenesis properties. Following that discovery the pharmaceutical industry has been hot on the trail of drugs which may be patentable and have these characteristics.Anti-angiogenesis drugs,angiostatin in treatment of cancer,endostatin in treatment of cancer,plasminogen

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