Adult Onset Diabetes (Type II Diabetes)
The subject of adult onset diabetes is one we should all take seriously. It is extremely common and is determined much more
by one’s diet over the years than by genetics (unlike childhood onset diabetes in which the opposite is the case). We are all
at risk for AOD which is nothing more than "insulin resistance."
For reasons we do not yet fully understand, the cells of the body partially shut down their insulin recognition systems.
Although plenty of insulin is onboard, it is not allowed to function as insulin is supposed to function. The function of insulin is
to open the cellular gates to the absorption of glucose. When this is not happening, the blood level of glucose builds up which
causes the pancreas to overproduce insulin in an effort to bring down the blood level of glucose. This results in the
overproduction of insulin. This excess insulin then acts as a toxin for the rest of the body.
Here are the effects of excess insulin:
- Proliferation of cells in the walls of arteries, hastening the onset of vascular disease
- Abdominal obesity (conversion of glucose to fat and storage of the fat)
- Adverse blood chemistry changes, to wit:
- Increased cholesterol, triglycerides, and uric acid
- Decreased HDL
The complex of symptoms above was first delineated in 1988 and named "Syndrome X," meaning that it was not understood. We now understand that it is caused by the effects of too much insulin on the biochemistry of the body. Syndrome X is the clinical manifestation of AOD.
The appearance of Syndrome X greatly accelerated with the introduction of aspartame, also known by the brand name
Nutrasweet. The average American consumes 148 pounds of artificial sweetener each year, most of it aspartame. By the
way, the metabolism of aspartame includes the production of methyl alcohol (methanol), a dangerous liver toxin. But, never
fear, the FDA tells us it is perfectly safe. I would love to see the money trail on that one.
You are predisposed to develop Syndrome X (AOD) by:
- Increased fat intake
- Increased intake of "high glycemic" complex carbohydrates (breads, pastas, pastries—these are digested to simple sugars quickly, and simple carbs such as that found in candy and soda pop)
- Decreased intake of "low glycemic" complex carbohydrates (these are digested to simple sugars slowly)
- Decreased exercise
- Deficiency of the following nutrients:
- Trace minerals in general
- Deficiency of protein and an imbalance of carbohydrate to protein ratio (should be about 10:7 with the carbs being high glycemic complex carbs)
The reversal of Syndrome X and AOD is, obviously, to reverse all the above factors. This should be done in partnership
with a knowledgeable and experienced medical doctor, one who practices nutritional medicine.
Items which are useful in the treatment of AOD which are not actually deficient are vitamin E, lipoic acid, vanadyl sulfate, and
chromium picolinate, as well as a good multivitamin and multi mineral supplement. Another highly effective treatment for late
stage diabetes (when insulin production is below normal) is the herb Gymnema sylvestre which helps to regenerate non-
functional beta cells (the cells which produce insulin).
Other important treatments include flax oil, niacin, niacinamide, pyridoxine, biotin, vitamins C, E, K, B6, B12, and minerals
zinc, manganese, copper, and magnesium, DHEA. Also, chelation therapy typically reduces the insulin requirement
dramatically in the insulin diabetic and has a positive effect on all cases of diabetes.
Finally, nothing is more important in treating diabetes than exercise. Pumping iron into the anaerobic range (when it hurts)
builds more insulin receptors and goes a long way toward correcting the root problem of adult onset diabetes: insulin
- Regelson W et al. Hormone intervention: "Buffer hormones" or "state dependency." The role of dehydroepiandosterone (DHEA), thyroid hormone, estrogen and hypophysectomy in aging. Annals New York Acad of Sci 1988;521:260-273.
- Bulbrook RD et al. Relation between urinary androgen and corticoid excretion and subsequent breast cancer. Lancet 1971;ii:395-398.
- Barrett-Conner E et al. A prospective study of de-hydroepiandosterone sulfate, mortality and cardiovascular disease. New Eng J Med 1986;315(24): 1519-1524.
- Lee JR Natural Progesterone: The Multiple Roles of a Remarkable Hormone BLL Publishing, Sebastopol, CA 1993
- Nelson DR, Zhang Y, Hannan MT, et al. The effect of postmenopausal estrogen therapy on bone density in elderly women. N Eng J Med 1993;329:1141-1146.
- Prior JC, Vigna YM Spinal bone loss and ovulatory disturbances. N Engl J Med 1990;223:1221-1227.
- Reported in article Sperm-count drop tied to pollution rise. Medical Tribune 1992;March 26
- Rudy DR Hormone replacement therapy. Postgraduate Medicine 1990;Dec.:157-164.
- Johansen JS, Jensen SB, Riis BJ, et al. Bone formation is stimulated by combined estrogen, progestagen. Metabolism 1990;39:1122-1126.
- Kleerekoper ME, Peterson E, Phillips E, Nelson D, et al. Continuous sodium fluoride therapy does not reduce vertebral fracture rate in postmenopausal osteoporosis [abstract] J Bone Miner Res 1989;Res 4 (Suppl. 1):S376.
- Follingstad AH Estriol. The forgotten estrogen? JAMA Jan. 2 1978;Vol 239, No. 1:29-30.
- Rudman D, et. al Effects of human growth hormone in men over sixty years old The New Engl J of Med July 5, 1990; vol 323:1-5.
- Hall K, Sara VR Somatomedin levels in childhood, adolescence, and adult life J Clin Endocrinol Metab 1984; 13:91-112.
- Cynober L Can arginine and ornithine support gut function? Gut 1994; suppl. 1:S12-S15.
- Welbourne TC Increased plasma bicarbonate and growth hormone after oral glutamine load. Am J Clin Nutr 1995; 61:1058-1061.
- Reaven GM Role of insulin resistance in human diabetes. Diabetes 37:1595-1607, 1988.
- Kaplan NM The deadly quartet: upper body obesity, glucose intolerance, hypertriglyceridemia, and hypertension Arch Int Med 149:1514-20, 1989.
- Karhapaa P, et. al Isolated low HDL cholesterol, an insulin resistant state Diabetes 43:411-17, 1994.
- Bjorntorp P, et. al The effect of physical training on insulin production in obesity Metabolism 19:631, 1970.
- Rizza RA, et. al Production of insulin resistance by hyperinsulinemia in man Diabetologia 28:70-75, 1985.
- O’Dea K Marked improvement in carbohydrate and lipid metabolism in diabetic Australian Aborigines after temporary reversion to traditional lifestyle Diabetes 33:596-603, 1984.
- Baird I Safety of liquid-protein diets Lancet 1;1979:618
- Annals of Nutrition Metab 1995;39:217-23
- Experimental and Clinical Endocrinology and Diabetes 1995;104:126-127
- Journal of Ethnopharmacology 1990;30:265-79 / 281-94 / 295-300