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Questions for Dr. Kennedy
Welcome to Ask Dr. Kennedy. We encourage you to post your comments and questions here. We look forward to challenging questions as they are an education for us as well as for you. Please consider the following guidelines when posting:

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Muckle-Wells Syndrome
Posted by: gina
Date: February 28, 2000 5:04 AM

I have a cousin who is 12 years old who has been diagnosed with having Muckle-Wells Syndrome. Do you have information on this problem?

Muckle-Wells Syndrome
Posted by: Ron Kennedy,MD
Date: February 29, 2000 2:43 PM

Muckle-Wells syndrome is urticaria, deafness, and amyloidosis. This is an autosomal dominant condition with recurrent fever, skin rash (urticaria), joint pain, progressive sensorineural hearing loss, and amyloidosis of the kidneys, which is an accumulation of a protein in the kidney which gradually blocks its function. The hearing loss usually begins in childhood, while the other problems may not be seen until adolescence.

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