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Questions for Dr. Kennedy
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DMPS reaction?
Posted by: Lane
Date: May 18, 2004 7:15 PM

I've been under the care of a knowledgeable physician for mercury/aluminum removal. We have used DMSA and DMPS. My mercury level was 29.55 ug/24-hour after the DMSA protocol and one DMPS IV. Yesterday was my fifth (and hopefully final) DMPS chelation treatment. I just completed the 2nd (and hopefully final) urine challenge today. I had the DMPS IV yesterday at 2:00 PM. I woke up at 5:00 AM this morning feeling very nauseous and have had severe diarhea and nausea the whole day which is most unusual for me. I didn't have any reaction at all from the other 4 DMPS IVs. Do you think this is the mercury or aluminum coming out? It could be food poisoning but I didn't eat anything suspect yesterday, unless something at the salad bar was rancid.

RE: DMPS reaction?
Posted by: Ron Kennedy, M.D.
Date: May 19, 2004 1:48 AM

Impossible to know for sure, but with severe nausea and diarrhea all day, the most likely explanation is food poisoning. The exit of heavy metals usually does not involve nausea and diarrhea (more often headache and fatigue) and should be most severe in the first 6-8 hours. The next thing to consider is an allergic reaction to DMPS (but again the reaction should be more proximate to the infusion of DMPS). You could have your doctor give you an epidermal injection of 0.03 cc of DMPS and if this causes a flair reaction, you will know that you have developed an allergy. If this is so, obviously no further DMPS should be used on you - which is OK as oral DMSA will do the job just fine anyway.

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