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Questions for Dr. Kennedy
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Hypothyroidism over 40
Posted by: Julie
Date: January 14, 2002 2:06 AM

I have been diagnosed with hypothyroidism for the last three years and have been taking Armour thyroid 2 grains. I have recently been reading your site. I see that you believe that over the age of 40, Armour is not the proper thyroid replacement. My doctor has tried giving me thyroxine (T4) alone, and I have the reaction of swelling up and delveloping "phantom" itchyness on my forearms so badly I will claw at them in my sleep until they bleed. Once again I am on the Armour. My doctor has agreed to give me T3 if I can find a compounding pharmacy to make it slow release. I have found such a pharmacy in my area. Would the ratio of T3 I would have them make equal the amount of T3 I am now taking in the 2 grains of Armour?



Edited 4 time(s). Last edit at October 28, 2007 10:09 PM by Dr. Kennedy.

RE: Hypothyroidism over 40
Posted by: Ron Kennedy, M.D.
Date: January 14, 2002 2:40 AM

The problem with T4 over age 40 is that increasingly most people cannot fully convert T4 to T3 which is the active form of thyroid hormone. Naturally, plain T4 would not be too useful for such a person. I prefer 12 hour Time Release T3 given every 12 hours as it mimics the physiology of the thyroid better than anything else. As to dosage, it would probably end up higher than the amount you are receiving with Armour, but starting at that level would be a reasonable thing to do, then adjust according to clinical response and lab tests. The best lab test is 24 hour urine collection for Free T3 from Genova Diagnostics. Also, Serum TSH is important.



Edited 2 time(s). Last edit at October 28, 2007 10:10 PM by Dr. Kennedy.



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