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Questions for Dr. Kennedy
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DHEA falling despite treatment
Posted by: Barbara
Date: November 4, 2001 12:07 AM

Three months ago I was diagnosed as having adrenal insufficiency. My cortisol levels throughout the day were low range and below range, as were my DHEA levels. I was prescribed 10 mg. hydrocortisone per day and 10 mg. twice a day of DHEA. My latest test results show that my cortisol levels have come up slightly to within the range, but my DHEA levels have dropped and now are nearly a flat line at the bottom of the graph. My doctor is baffled and has raised my DHEA prescription to 25 mg. twice a day to give him time to consider the next test.Could you please suggest any reasons for the fall in DHEA levels?

RE: DHEA falling despite treatment
Posted by: Ron Kennedy, M.D.
Date: November 4, 2001 5:31 PM

Well, if you poured a pitcher of water into a stream and it quickly diappeared, where would it have gone? Downstream, right? What is downstream from DHEA? The sex steroids: estrogens, testosterone and the intermediates as well as the metabolites.

RE: DHEA falling despite treatment
Posted by: Barbara
Date: November 5, 2001 9:26 PM

Thank you so much for taking the time to answer my question on a Sunday. Would you think a bigger pitcher would do the trick, or should I try to persuade someone to take a look at what's happening downstream?

RE: DHEA falling despite treatment
Posted by: Ron Kennedy, M.D.
Date: November 6, 2001 12:00 AM

I always supplement small amounts at many places along the line of hormones as they work themselves downstream rather than a large amount of an upstream hormone. However if one is going to supplement only one, it should be upstream.



This Thread has been closed

 




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