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Questions for Dr. Kennedy
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Adenosine Monophosphate (AMP) injections
Posted by: Piper
Date: August 22, 2001 5:20 AM

I have a friend who goes to a weight loss clinic and she is taking hCG (Human Chorionic Gonadotropin) injections daily and has lost 60 pounds in 4-1/2months. She also takes Bontril SR for appetite control. She called and told me they are offering a new injection called Adenosine Monophosphate twice a week and that it's used to treat Chronic Fatigue Syndrome and Fibromyalgia. She has neither condition. The flyer she has said that "While treating patients with CFS and FM researchers discovered an unexpected side effect. The patients had a noticeable reduction in their waistlines and other areas as well." It also states "Further research led to the discovery that the adenosine actually has a cellular level effect on the body, causing fat cells to release their stored fat to be burned as energy." There is also some B12 and B6 in the shot. What is your take on this? Is it safe? Could she die from this? It states that it doesn't make you lose pounds but inches rather... how can this be?

Adenosine Monophosphate (AMP) injections
Posted by: Ron Kennedy, M.D.
Date: August 22, 2001 1:17 PM

AMP is a precursor to ADP and ATP (adenosine di-phosphate and adenosine tri-phosphate) which are final storage forms of energy in the mitochondria of muscle and nerve tissue. When you move muscle or think you use up some of your stored ATP and if you over-exercise you begin to use up your ADP. AMP helps to restore the supply. Safety, as with any substance, is dose related. An occasional side-effect of AMP is rapid heartbeat. For this reason it is given in two smaller divided dose. If it is accidentally injected into a vein (about one out of every 600 IM injections) the tachycardia is dramatic and alarming, but as far as I know not fatal in proper dose. It is conceivable that weight redistribution could happen with AMP use as it in effect speeds metabolism selectively in muscle tissue, thus simulating a muscular workout. B6 and B12 are safe in proper dose and even in large doses and would assist in fat burning. However, the base cause of excess weight is one or both of the following: food addiction and hypometabolism. If these base causes are not corrected weight gain will follow weight loss as surely as night follows day.



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