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Questions for Dr. Kennedy
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hydrogen peroxide and catalase enzymes
Posted by: Christopher
Date: July 19, 2001 1:28 PM

In IV hydrogen peroxide therapy, what happens in the reaction between hydrogen peroxide in the body and catalase enzymes from the liver. How does it happen, why does it happen and what is involved?

RE: hydrogen peroxide and catalase enzymes
Posted by: Ron Kennedy, M.D.
Date: July 19, 2001 2:30 PM

Catalase is also found in blood. It metabolizes H2O2 to water and oxygen. Also cytochrome-C is present. That part of infused hydrogen peroxide that binds with cytochrome-C is not allowed to become water and singlet oxygen for a period of forty minutes. After forty minutes of being bound to cytochrome-C this enzyme begins to act like catalase and breaks down the hydrogen peroxide to water and singlet oxygen. By this time, the hydrogen peroxide/cytochrome-C complex has been spread throughout the body. In this way the benefits of hydrogen peroxide are made available to all cells. About 50% goes to each enzyme system after infusion.



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