Fatal Familial Insomnia (FFI)
Fatal familial insomnia (FFI) is a hereditary prion disease with disrupted sleep (insomnia), motor abnormalities (myoclonus, ataxia, dysarthria, dysphagia, and pyramidal signs), and hyperactivation of the autonomic nervous system. It is due to a mutation of the prion protein gene on chromosome 20. There is a fatal form of this disorder. One more thing to worry about.