Factor VIII (Antihemophiliac Factor) (Antihemophiliac Globulin)
Factor VIII is a protein which is a key factor in the process of blood coagulation. Lack of normal factor VIII causes hemophilia (hemophilia A, classic hemophilia. The gene for classic hemophilia is on the X chromosome. Females carry the gene and transmit it to their hemophiliac sons. Female carriers are normal because they have another X chromosome that contains a normal gene to make factor VIII. Each of their sons has a 50% risk of being a hemophiliac. Factor VIII is also known as antihemophiliac factor or antihemophiliac globulin.