Cortico-basal Degeneration (CBD)

Cortico-basal Degeneration (CBD)

Dr. Kennedy
This is a degenerative disorder of the brain. The cause of CBD is said to be unknown. There is currently no strong evidence to suggest CBD is an inherited disease, and no other risk factors, such as toxins or infections, have been identified. However, this is probably because heavy metals are not properly evaluated in mainstream medicine. Proper evaluation requires a “stimulation test” using a chelating agent followed by urine analysis for metals.

Studies of brain tissue of individuals with CBD show certain characteristic cell changes. Similar, although not identical, changes are observed in two other neurodegenerative diseases, Pick’s disease and progressive supranuclear palsy. These changes involve a class of brain protein called tau, which are microtubule-associated proteins abundant in neurons in the central nervous system and are less common elsewhere. They were discovered in 1975 at Princeton University. Tau proteins interact with tubulin to stabilize microtubules and promote tubulin assembly into microtubules. Six tau isoforms exist in brain tissue.

Suspect this diagnosis when a high percentage of these symptoms appear:

  • Unilateral symptoms – initially may be one-sided
  • Bilateral symptoms – as disease progresses both sides affected
  • Poor coordination
  • Akinesia (absence of movements)
  • Rigidity
  • Impaired balance
  • Limb dystonia (abnormal muscle postures)
  • Cognitive impairment
  • Visual-spatial impairment
  • Apraxia
  • Hesitant and halting speech
  • Myoclonus
  • Dysphagia (difficulty swallowing)
  • Difficulty walking
  • Poor coordination
  • Speech difficulty
  • Swallowing difficulty

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