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The Hunger Project Bolen Report
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Bowen's Disease (Squamous Cell Carcinoma in situ) Print E-mail

Dr. Kennedy Bowen's disease is an early stage of skin cancer. It is medically the same as "squamous cell carcinoma in situ." Squamous cell carcinoma is a tumor that develops from the squamous cells which are flat, scale-like cells in the outer layer of the skin (the epithelium). The term "in situ" (Latin) means "in the natural or normal place" and, in the case of cancer, it says that the tumor cells are still confined to the site where they originated and they have neither invaded neighboring tissues nor metastasized afar. The hallmark of Bowen's disease is a persistent, progressive, slightly raised, red, scaly or crusted plaque. Bowen disease may occur anywhere on the skin surface (or on mucosal surfaces such as in the mouth). Under the microscope, atypical squamous cells are seen to have proliferated through the whole thickness of the epidermis (the outer layer of the skin) but to have gone no farther. The cause of Bowen's disease classically was prolonged exposure to arsenic. Today, Bowen's disease occurs most often in the sun-exposed areas of the skin in older white males.



The information in this article is not meant to be medical advice.�Treatment for a medical condition should come at the recommendation of your personal physician.

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