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Biermer's Anemia (Pernicious Anemia) (B12 Deficiency) Print E-mail

Dr. Kennedy Biermer's anemia is a blood disorder caused by a lack of vitamin B12. Patients who have this disorder do not produce the substance in the stomach that allows the body to absorb vitamin B12. This substance is called intrinsic factor. Biermer's anemia, better known as pernicious anemia, is characterized by the presence in the blood of large, immature, nucleated cells (megaloblasts) that are forerunners of red blood cells. (Red blood cells, when mature, have no nucleus). It is thus a type of megaloblastic anemia. Nowadays PA is an unpernicious anemia. It is simply treated with vitamin B12. The vitamin B12 has to be administered by injection (parenterally) because people with PA do not have intrinsic factor (or an effective form of intrinsic factor) and so cannot absorb vitamin B12 taken by mouth.



The information in this article is not meant to be medical advice.�Treatment for a medical condition should come at the recommendation of your personal physician.

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