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Bacterial Artificial Chromosome (BAC) Print E-mail

Dr. Kennedy Bacterial artificial chromosomes are created in a laboratory and the methodology involves an artificially constructed or extracted (from another species) chromosome in which medium-sized segments of DNA (100,000 to 300,000 bases in length) that come from another species are cloned into bacteria. Once the foreign DNA has been cloned into the bacteria's chromosome, many copies of it can be made (amplified) and sequenced. An example of this is the commercial production of human growth hormone. A human gene is spiced into E coli and the bacteria make the HGH which is then harvested and purified. Bacterial artificial chromosome is abbreviated BAC.



The information in this article is not meant to be medical advice.�Treatment for a medical condition should come at the recommendation of your personal physician.

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