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The Hunger Project Bolen Report
Ohm Society
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Anticipation Print E-mail
by Ron Kennedy, M.D., Santa Rosa, CA

Dr. Kennedy "Anticipation" describes a remarkable phenomenon in which a genetic disease appears earlier and with increased intensity with each succeeding generation. Anticipation was once thought not to exist in genetics. However, it has now been proven to occur in a large number of important genetic disorders, including Huntington's disease and myotonic dystrophy. In molecular terms, anticipation is due to the expansion of a trinucleotide repeat sequence in the DNA. This phenomenon also occurs in the fragile X syndrome, the most common inherited form of mental retardation.



The information in this article is not meant to be medical advice.�Treatment for a medical condition should come at the recommendation of your personal physician.

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