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Inositol Hexa-niacinate (a.k.a. IHN) Print E-mail
by Ron Kennedy, M.D., Santa Rosa, CA

Dr. Kennedy This nifty molecule is make of inositol, which lowers cholesterol all by itself, with six niacin molecules attached. It has long been appreciated that niacin will lower cholesterol by accelerating its metabolism, but use of niacin has been limited by the "flush reaction." About 30-60 minutes after any significant dose of niacin, the face turns beet red and becomes hot as a firecracker. This then spreads to the chest and abdomen. This reaction demonstrates niacin's ability to dilate blood vessels, but makes taking it too uncomfortable for most people. It also limits dosages to the relatively non-therapeutic range. With inositol hexa-niacinate, this flush is almost non-existent as the niacin is slowly released. This allows therapeutic doses of 2-4 grams per day to be easily reached. Liver enzyme studies should be done four weeks after therapy begins to be certain that large doses of niacin can be handled by the individual.



The information in this article is not meant to be medical advice.�Treatment for a medical condition should come at the recommendation of your personal physician.

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