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Cox-2 (Cyclooxygenase-2), Cox-2 Inhibitor Print E-mail

Dr. Kennedy Cox-2 (Cyclooxygenase-2) is a protein that acts as an enzyme and specifically catalyzes (speeds) the production of certain chemical messengers called prostaglandins. Some of these messengers are responsible for promoting inflammation. When Cox-2 activity is blocked, inflammation is reduced. Unlike cox-1, cox-2 is active only at the site of inflammation, not in the stomach.

A cox-2 inhibitor: is a type of drug that selectively blocks the enzyme cox-2 (cyclooxygenase-2). Blocking this enzyme impedes the production of the chemical messengers called prostaglandins that cause the pain and swelling of arthritis inflammation. Cox-2 inhibitors may not pose as great a risk of injuring the stomach or intestines as cox-1 inhibitors. Cox-2 inhibitors now on the market include celecoxib (brand name: Celebrex) and rofecoxib (brand name: Vioxx).

Unfortunately, It has been found that Celebrex, like the other COX-2 inhibitors Vioxx and Bextra increases the risk of heart attacks by 2.5 times, as well as strokes and blood clots.



The information in this article is not meant to be medical advice.�Treatment for a medical condition should come at the recommendation of your personal physician.

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