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Chimeraplasty Print E-mail

Dr. Kennedy Chimeraplasty is a method of gene therapy based upon the use of a molecule called a chimeraplast, a synthetic blend of DNA and the related molecule RNA, to trick the patient's own cells to remedy a gene defect. Chimeraplasts are made to match the patient's sequence of base pairs (the molecular building blocks of DNA), except in one area, the area of the mutation (the change) that is responsible for the gene defect. There, the chimeraplasts have the correct sequence of base pairs in the DNA. The chimeraplasts are designed to attach to the patient's DNA and activate the DNA repair system, a system that cells normally use to correct mistakes they make in replicating their DNA. The patient's DNA repair system is tricked into treating the chimeraplast as the correct version of the DNA and changing the patient's gene to match the chimeraplast, thus correcting the mutation.



The information in this article is not meant to be medical advice.�Treatment for a medical condition should come at the recommendation of your personal physician.

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